Acupuncture and related techniques for restless legs syndrome: A protocol for systematic review and meta-analysis. Issue 39 (25th September 2020)

• Record Type: Journal Article
• Authors: Xiang, Jie; Li, Honglian; Xiong, Jun; Hua, Fanghui; Huang, Shouqiang; Jiang, Yunfeng; Qiang, Hailiang; Xie, Fan; Wang, Min
• Is Part Of: Medicine. Volume 99:Issue 39(2020)
• Publication Date: 2020-09-25
• Subjects: acupuncture -- protocol -- restless legs syndrome -- systematic review; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000022205
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract: Background: Restless legs syndrome (RLS) is a common sensory disorder of the nervous system, which often affects the sleep quality of patients. Acupuncture and related techniques are increasingly used to treat neurological diseases, but their efficacy and safety for RLS are yet to be established. The purpose of this study is to summarize the effectiveness and safety of acupuncture and related techniques for RLS. Methods: We will conduct a comprehensive data retrieval, and the electronic databases will include PubMed, Embase, Cochrane Library, WangFang Database, China National Knowledge Infrastructure, Chinese Scientific Journal Database, Chinese Biomedical Literature Database, from establishment to October 2020. We will also manually search unpublished studies and references, and contact lead authors. Randomized clinical trials (RCTs) of acupuncture and related techniques for RLS will be included. The outcomes of interest include: The total effective rate and International Restless Leg Syndrome rating scale (IRLS), Pittsburgh Sleep Quality Index (PSQI), Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD), adverse events, quality of life. To assess the methodological quality, we will use the Cochrane risk assessment tool. RevMan 5.3.5 software will be used to conduct data synthesis. The evidence quality of each outcome will be appraised according to Grades of Recommendation, Assessment, Development, and Evaluation (GRADE). Results: The results will be published in a peer-reviewed journal. Conclusion: This study will provide a high-quality evidence to evaluate the efficacy and adverse reactions of acupuncture and related techniques for RLS. PROSPERO registration number: CRD42020157957.