Paracrine WNT5A signaling in healthy and neoplastic mammary tissue. (2nd January 2016)
- Record Type:
- Journal Article
- Title:
- Paracrine WNT5A signaling in healthy and neoplastic mammary tissue. (2nd January 2016)
- Main Title:
- Paracrine WNT5A signaling in healthy and neoplastic mammary tissue
- Authors:
- Kusner, David
Borcherding, Nicholas
Zhang, Weizhou - Abstract:
- ABSTRACT: Paracrine signaling between mammary epithelial cells has long been appreciated. Recently, we found that Wnt5a, a novel noncanonical Wnt ligand of luminal origin, counteracts canonical Wnt signaling in basal mammary epithelial cells through a paracrine pathway, inhibits the expansion of Erbb2-induced tumor-initiating cells, and suppresses tumor incidence and metastasis.
- Is Part Of:
- Molecular & cellular oncology. Volume 3:Number 1(2016)
- Journal:
- Molecular & cellular oncology
- Issue:
- Volume 3:Number 1(2016)
- Issue Display:
- Volume 3, Issue 1 (2016)
- Year:
- 2016
- Volume:
- 3
- Issue:
- 1
- Issue Sort Value:
- 2016-0003-0001-0000
- Page Start:
- Page End:
- Publication Date:
- 2016-01-02
- Subjects:
- Breast cancer -- mammary development -- Noncanonical WNT -- WNT5A signaling
Tumors -- Periodicals
Neoplasms
Periodicals
616.99 - Journal URLs:
- http://www.tandfonline.com/loi/kmco20#.VyIIeFL2aic ↗
http://www.tandfonline.com/ ↗ - DOI:
- 10.1080/23723556.2015.1040145 ↗
- Languages:
- English
- ISSNs:
- 2372-3556
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 14530.xml