Longitudinal association between eating frequency and hemoglobin A1c and serum lipids in diabetes in the SEARCH for Diabetes in Youth study. Issue 6 (31st May 2018)

• Record Type: Journal Article
• Authors: Li, Chao; D'Agostino, Ralph B; Dabelea, Dana; Liese, Angela D; Mayer‐Davis, Elizabeth J; Pate, Russell; Merchant, Anwar T
• Is Part Of: Pediatric diabetes. Volume 19:Issue 6(2018)
• Page Start: 1073
• Page End: 1078
• Publication Date: 2018-05-31
• Subjects: diabetes -- eating frequency -- longitudinal analysis and nutrition -- youth; Diabetes in children -- Periodicals; 616.462
• DOI: 10.1111/pedi.12690
• Languages: English
• ISSNs: 1399-543X

Abstract

Abstract : Background: Few studies have evaluated the prospective association of eating frequency with HbA1c levels and cardiovascular disease risk markers among youth with diabetes. Objective: To examine the 5‐year longitudinal association of eating frequency with HbA1c and serum lipid levels among youth with type 1 diabetes (T1D) or type 2 diabetes (T2D). Methods: One‐thousand and forty‐nine youth (≥10‐year old) with incident T1D ( n = 821) or T2D ( n = 228) who participated in the SEARCH for Diabetes in Youth study were included. Eating frequency (≤3, 4‐5, or 6‐10 times/d) measured at baseline and follow‐up visits was related to HbA1c and serum lipid levels measured repeatedly over 5 years. Results: Increased eating frequency was associated with larger increases in HbA1c among youth T1D. For example, for youth with T1D who ate ≤3 times/d at the outset and ate 6‐10 times/d 5 years later, the longitudinal model predicted greater absolute increases in HbA1c (2.77%); whereas for youth with T1D who ate 6‐10 times/d at the outset and ate ≤3 times/d 5 years later, the model predicted lesser absolute increases in HbA1c (1.33%). Eating frequency was not associated with changes in serum lipid levels among youth with T1D or T2D. Conclusions: Youth with T1D who increased their eating frequency vs those who decreased it had larger increases in HbA1c over 5 years.