A face identity hallucination (palinopsia) generated by intracerebral stimulation of the face-selective right lateral fusiform cortex. (February 2018)

• Record Type: Journal Article
• Authors: Jonas, Jacques; Brissart, Hélène; Hossu, Gabriela; Colnat-Coulbois, Sophie; Vignal, Jean-Pierre; Rossion, Bruno; Maillard, Louis
• Is Part Of: Cortex. Volume 99(2018)
• Page Start: 296
• Page End: 310
• Publication Date: 2018-02
• Subjects: SEEG -- Electrical brain stimulation -- Palinopsia -- Face perception -- Fusiform face area; Neuropsychology -- Periodicals; Nervous system -- Periodicals; Neurology -- Periodicals; Psychophysiology -- Periodicals; Behavior -- Periodicals; Neurology -- Periodicals; 612.825
• DOI: 10.1016/j.cortex.2017.11.022
• Languages: English
• ISSNs: 0010-9452

Abstract

Abstract: We report the case of a patient (MB, young female human subject) who systematically experienced confusion between perceived facial identities specifically when electrically stimulated inside the lateral section of the right fusiform gyrus. In the presence of a face stimulus (an experimenter or a photograph), intracerebral electrical stimulation in this region generated a perceptual hallucination of an individual facial part integrated within the whole perceived face, i.e., facial palinopsia. In the presence of a distracting stimulus (visual scene or object picture), the patient also experienced an individual face percept superimposed on the non-face stimulus. The stimulation site evoking this category-selective transient palinopsia was localized in a region showing highly selective responses to faces both with functional magnetic resonance imaging ("Fusiform Face Area", "FFA") and intracerebral electrophysiological recordings during fast periodic visual stimulation (FPVS). Importantly, the largest electrophysiological response to fast periodic changes of facial identity was also found at this location. Altogether, these observations suggest that the face-selective right lateral fusiform gyrus plays a role in generating vivid percepts of individual faces, supporting the active role of this region in individual face representation. Highlights: Electrical stimulation of the right FG evoked face identity hallucination. This region is highly face-selective and sensitive to individual faces. This supports a causal role of this region in individual face representation.