Three-component reaction of N-isocyaniminotriphenylphosphorane (Ph3PNNC), biacetyl, and a carboxylic acid in water. (3rd March 2016)

• Record Type: Journal Article
• Authors: Jafari, Ali; Ramazani, Ali; Ahankar, Hamideh; Asiabi, Pegah Azimzadeh; Sadri, Fariba; Joo, Sang Woo
• Is Part Of: Phosphorus, sulfur, and silicon and the related elements. Volume 191:Number 3(2016)
• Page Start: 373
• Page End: 380
• Publication Date: 2016-03-03
• Subjects: N-isocyaniminotriphenylphosphorane (Ph3PNNC) -- water -- 1, 3, 4-oxadiazoles -- aza-Wittig reaction -- carboxylic acid; Sulfur compounds -- Periodicals; Organosulfur compounds -- Periodicals; Phosphorus compounds -- Periodicals; Organophosphorus compounds -- Periodicals; Silicon compounds -- Periodicals; Organosilicon compounds -- Periodicals; 546
• DOI: 10.1080/10426507.2015.1091826
• Languages: English
• ISSNs: 1042-6507

Abstract

GRAPHICAL ABSTRACT: ABSTRACT: Reaction of N -isocyaniminotriphenylphosphorane with biacetyl in the presence of a carboxylic acid in water proceeds smoothly at RT (20–26°C) and neutral conditions to afford sterically congested 1, 3, 4-oxadiazole derivatives in high yields. The reaction proceeds smoothly and clearly under mild conditions and no side reactions were observed.