Anthracosis Mimicking Mediastinal Lymph Node Metastases With 18F-FCholine in High-Risk Prostate Cancer. (April 2015)

• Record Type: Journal Article
• Authors: Pinaquy, Jean-Baptiste; Fernandez, Philippe; Pasticier, Gilles; Parrens, Marie; De Clermont, Henri
• Is Part Of: Clinical nuclear medicine. Volume 40:Number 4(2015)
• Publication Date: 2015-04
• Subjects: anthracosis -- false positive -- fluorocholine -- metastasis -- PET -- prostate cancer; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000000707
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: A 62-year-old patient with prostate adenocarcinoma underwent PET with radiolabeled choline ( 18 F-Fcholine) for pretreatment staging of a high-risk prostate cancer. Images showed a significant mediastinal lymph node uptake of 18 F-Fcholine. Owing to the rarity of spread to supradiaphragmatic lymph nodes, a surgical removal was performed, revealing anthracosis and no malignant cells. Even if its specificity seems better than 18 F-FDG, false positives have been reported and other pathologies could mimic lymph node metastases. Consequently, histology should be performed so that the appropriate treatment can be initiated.