COMPARISON OF VISUAL PROGNOSES BETWEEN NATURAL COURSE OF SIMPLE HEMORRHAGE AND CHOROIDAL NEOVASCULARIZATION TREATED WITH INTRAVITREAL BEVACIZUMAB IN HIGHLY MYOPIC EYES: A 1-Year Follow-up. Issue 3 (March 2015)

• Record Type: Journal Article
• Authors: Goto, So; Sayanagi, Kaori; Ikuno, Yasushi; Jo, Yukari; Gomi, Fumi; Nishida, Kohji
• Is Part Of: Retina. Volume 35:Issue 3(2015:Mar.)
• Publication Date: 2015-03
• Subjects: high myopia -- subretinal hemorrhage -- simple hemorrhage -- choroidal neovascularization -- bevacizumab; Retina -- Diseases -- Periodicals; Retinal Diseases; Vitreous Body; 617.735
• DOI: 10.1097/IAE.0000000000000332
• Languages: English
• ISSNs: 0275-004X

Abstract

Abstract : Purpose: To compare the long-term outcomes of simple hemorrhage (SH) without any treatments and myopic choroidal neovascularization (mCNV) treated with intravitreal bevacizumab in highly myopic eyes. Methods: Twenty eyes (17 patients) with SH and 28 eyes (27 patients) with mCNV were included. We retrospectively evaluated the refractive error, axial length, age, best-corrected visual acuity, and the integrity of photoreceptor inner segment/outer segment junction and compared the two groups. Results: The mean patient age was 41.6 ± 11.2 years, the mean refractive error −12.7 ± 3.57 diopters, and the mean axial length was 29.64 ± 1.42 mm. Patients in the SH group were significantly ( P < 0.001) younger than those in the mCNV group (34.8 vs. 46.5 years, respectively). There were no significant differences in other parameters between the groups. Compared with baseline, the best-corrected visual acuity improved significantly ( P < 0.01) at 12 months in both groups. The change in vision at 12 months in the SH group was significantly ( P < 0.05) better than that in the mCNV group, although there were no significant differences at 3 months or 6 months. The final integrity of photoreceptor inner segment/outer segment junction was significantly associated with the final best-corrected visual acuity ( P < 0.05). Conclusion: Eyes with SH had a more favorable visual prognosis compared with eyes with mCNV treated with intravitreal bevacizumab. The differential diagnosis of these pathologies is important. Abstract : Simple hemorrhages in myopic eyes without choroidal neovascularization had better visual prognoses compared with eyes with myopic choroidal neovascularization. Even with the new anti-vascular endothelial growth factor treatment, eyes with simple hemorrhage have more favorable visual prognoses compared with eyes with myopic choroidal neovascularization treated with anti-vascular endothelial growth factor.