Stereoselective Synthesis of Z Fluoroalkenes through Copper‐Catalyzed Hydrodefluorination of gem‐Difluoroalkenes with Water. (22nd September 2017)
- Record Type:
- Journal Article
- Title:
- Stereoselective Synthesis of Z Fluoroalkenes through Copper‐Catalyzed Hydrodefluorination of gem‐Difluoroalkenes with Water. (22nd September 2017)
- Main Title:
- Stereoselective Synthesis of Z Fluoroalkenes through Copper‐Catalyzed Hydrodefluorination of gem‐Difluoroalkenes with Water
- Authors:
- Hu, Jiefeng
Han, Xiaowei
Yuan, Yu
Shi, Zhuangzhi - Abstract:
- Abstract: A copper catalytic system was established for the stereoselective hydrodefluorination of gem‐difluoroalkenes through C−F activation to synthesize various Z fluoroalkenes. H2 O is used as the hydrogen source for the fluorine acceptor moiety. This mild catalytic system shows good‐functional group compatibility, accepting a range of carbonyls as precursors to the gem‐difluoroalkenes, including aliphatic, aromatic, and α, β‐unsaturated aldehydes and even ketones. It serves as a powerful synthetic method for the late‐stage modification of complex compounds.
- Is Part Of:
- Angewandte Chemie. Volume 129:Number 43(2017)
- Journal:
- Angewandte Chemie
- Issue:
- Volume 129:Number 43(2017)
- Issue Display:
- Volume 129, Issue 43 (2017)
- Year:
- 2017
- Volume:
- 129
- Issue:
- 43
- Issue Sort Value:
- 2017-0129-0043-0000
- Page Start:
- 13527
- Page End:
- 13531
- Publication Date:
- 2017-09-22
- Subjects:
- Kupfer -- Fluor -- Fluoralkane -- Hydrodefluorierung -- Z-Selektivität
Chemistry -- Periodicals
540 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/ange.201708224 ↗
- Languages:
- English
- ISSNs:
- 0044-8249
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 0902.000000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 14503.xml