Pilomatrix Carcinoma in a Patient With Type 1 Myotonic Dystrophy: A Case Report. (8th January 2020)

• Record Type: Journal Article
• Authors: Zhu, Sarah L.; Choi, David; Santos, Jenny; Jackson, Bernard S.; McRae, Matthew
• Is Part Of: Plastic surgery. Volume 6(2020)
• Publication Date: 2020-01-08
• Subjects: pilomatrixoma -- pilomatrix carcinoma -- myotonic dystrophy -- myocutaneous flap; Surgery, Plastic -- Case studies -- Periodicals; Surgery, Plastic; Case studies; Periodicals; 617.952
• DOI: 10.1177/2513826X19898833
• Languages: English
• ISSNs: 2513-826X

Abstract

This is the first report of pilomatrix carcinoma in a man with C282Y myotonic dystrophy type 1. This pilomatrix carcinoma had originally presented as a rapidly growing recurrence of a histopathologically confirmed pilomatrixoma, removed a year prior. On examination, the fungating mass had measured 10 × 23 cm. A wide local resection with removal of suspicious lymph nodes was preformed, and the resulting defect was reconstructed with a latissimus dorsi myocutaneous flap and skin graft. Histologic investigation of the excised mass confirmed the diagnosis of pilomatrix carcinoma. This is the first reported case of pilomatrix carcinoma in a patient with a genetic condition that often presents with scalp pilomatrixomas. Potential implications of myotonic dystrophy on developing pilomatrix carcinoma are discussed.