Ticagrelor-Related Severe Dyspnoea: Mechanisms, Characteristic Features, Differential Diagnosis and Treatment. Issue 13 (October 2020)

• Record Type: Journal Article
• Authors: Krakowiak, Alicja; Kuleta, Jakub; Plech, Iwona; Zarębiński, Maciej; Wojciechowska, Małgorzata; Wretowski, Dominik; Cudnoch-Jędrzejewska, Agnieszka
• Is Part Of: Clinical medicine insights. Issue 13(2020)
• Publication Date: 2020-10
• Subjects: Ticagrelor -- dyspnoea -- bradycardia -- acute coronary syndrome; Clinical medicine -- Case studies -- Periodicals; Medicine; Clinical medicine; Electronic journals; Case Reports; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; Case studies; Periodicals; 616.09
• DOI: 10.1177/1179547620956634
• Languages: English
• ISSNs: 1179-5476

Abstract

With a growing number of patients on ticagrelor therapy after stent implantation, we observe many cases of side effects of the drug, mostly dyspnoea and bradycardia. In our article we present 2 patients, in which the symptoms were particularly severe. Then we describe possible mechanisms of these complications, explain how to carry out differential diagnosis, discuss when to switch ticagrelor to other antiplatelet drug and finally we present the way to deal with the symptoms.