Improvement of Blood Pressure Control by Adherence Check in Patients With Apparent Treatment-Resistant Hypertension: A Case Series. Issue 13 (February 2020)

• Record Type: Journal Article
• Authors: Hosohata, Keiko; Inada, Ayaka; Oyama, Saki; Doi, Takashi; Niinomi, Iku; Wakabayashi, Tomohito; Uchida, Mayako; Iwanaga, Kazunori; Matsuoka, Hiroyuki
• Is Part Of: Clinical medicine insights. Issue 13(2020)
• Publication Date: 2020-02
• Subjects: adherence to medication -- hypertension -- pharmacist; Clinical medicine -- Case studies -- Periodicals; Medicine; Clinical medicine; Electronic journals; Case Reports; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; Case studies; Periodicals; 616.09
• DOI: 10.1177/1179547620904884
• Languages: English
• ISSNs: 1179-5476

Abstract

Adherence to medications is an important challenge while treating chronic disease such as resistant hypertension, which is defined as uncontrolled blood pressure (BP) despite treatment with more than 3 antihypertensive drugs to achieve targets. It is possible that poor adherence is the most significant contributor to rates of pseudo-resistance among treated hypertensive patients. In this report, we describe 4 patients with apparent treatment-resistant hypertension, who received intervention to promote adherence by pharmacists who set the prescribed medicines in a weekly medication calendar and conducted a weekly pill count. The results showed that the intervention of pharmacists to medication adherence improved systolic BP in patients with apparent treatment-resistant hypertension; however, further controlled trials are required to strengthen supporting evidence.