Diet-delivered RNAi in Helicoverpa armigera – Progresses and challenges. (February 2016)

• Record Type: Journal Article
• Authors: Lim, Zhi Xian; Robinson, Karl E.; Jain, Ritesh G.; Sharath Chandra, G.; Asokan, R.; Asgari, Sassan; Mitter, Neena
• Is Part Of: Journal of insect physiology. Volume 85(2016:Feb.)
• Page Start: 86
• Page End: 93
• Publication Date: 2016-02
• Subjects: Helicoverpa armigera -- Cotton bollworm -- RNA interference -- RNAi -- Diet-delivery -- dsRNA uptake; Insects -- Physiology -- Periodicals; Insectes -- Physiologie -- Périodiques; Insects -- Physiology; Periodicals; 571.157
• DOI: 10.1016/j.jinsphys.2015.11.005
• Languages: English
• ISSNs: 0022-1910

Abstract

Graphical abstract: Highlights: Current knowledge on the fate of ingested dsRNA in Helicoverpa armigera is reviewed. In vivo studies on diet-delivered RNAi and their effects are summarized. Factors and hurdles affecting the efficacy of diet-delivered RNAi are discussed. Abstract: Helicoverpa armigera (the cotton bollworm) is a significant agricultural pest endemic to Afro-Eurasia and Oceania. Gene suppression via RNA interference (RNAi) presents a potential avenue for management of the pest, which is highly resistant to traditional insecticide sprays. This article reviews current understanding on the fate of ingested double-stranded RNA in H. armigera . Existing in vivo studies on diet-delivered RNAi and their effects are summarized and followed by a discussion on the factors and hurdles affecting the efficacy of diet-delivered RNAi in H. armigera .