Development of a highly selective colorimetric pyrophosphate probe based on a metal complex and gold nanoparticles: change in selectivity induced by metal ion tuning of the metal complex. Issue 35 (26th August 2015)

• Record Type: Journal Article
• Authors: Kim, Sudeok; Eom, Min Sik; Yoo, Soyeon; Han, Min Su
• Is Part Of: Tetrahedron letters. Volume 56:Issue 35(2015)
• Page Start: 5030
• Page End: 5033
• Publication Date: 2015-08-26
• Subjects: Gold nanoparticles -- Pyrophosphate -- Colorimetric -- Metal complex -- Selectivity; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2015.07.020
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Abstract: In this study, we developed a colorimetric sensing system for pyrophosphate (PPi) with a probe composed of phosphate functionalized-gold nanoparticles as the reporter unit and [Cu3 (1, 3, 5-tris[bis(pyridine-2-ylmethyl)aminomethyl]-2, 4, 6-triethylbenzene)] 6+ (2 ) as the receptor unit. The proposed probe allows easy detection of PPi with the naked eye, and selectively recognizes PPi with a detection limit of 320 nM. Unlike previous AuNP based-PPi sensing systems, this probe exhibits high selectivity for PPi over various other phosphate derivatives including adenosine triphosphate (ATP) and adenosine diphosphate (ADP).