Pulmonary capillary permeability and pulmonary microangiopathy in diabetes mellitus. Issue 3 (June 2015)

• Record Type: Journal Article
• Authors: Kuziemski, Krzysztof; Pieńkowska, Joanna; Słomiński, Wojciech; Jassem, Ewa; Studniarek, Michał
• Is Part Of: Diabetes research and clinical practice. Volume 108:Issue 3(2015)
• Page Start: e56
• Page End: e59
• Publication Date: 2015-06
• Subjects: DLCO lung diffusion capacity for carbon monoxide -- DLCO/VA lung diffusing capacity for carbon monoxide/alveolar volume -- FEV1 forced expiratory volume in one second -- pCT perfusion chest computed tomography -- MTT mean transit time -- PS permeability surface -- ROI regions of interest -- TLC total lung capacity -- VC vital capacity -- PFT pulmonary function test; Perfusion CT -- Lung microangiopathy -- Diabetes mellitus -- Lung function tests; Diabetes -- Periodicals; Diabetes Mellitus -- Periodicals; 616.462
• DOI: 10.1016/j.diabres.2015.02.033
• Languages: English
• ISSNs: 0168-8227

Abstract

Highlights: Pulmonary microangiopathy alters structure and function of pulmonary capillaries. The use of pCT offers new ways for imaging of pulmonary vessels and parenchyma. Anomalies in pulmonary perfusion help to diagnose respiratory complications of DM. We evaluated four perfusion parameters for their diagnostic usefulness. Of those, PS is the most useful for assessing pulmonary microcirculation in DM. Abstract: Significant increase in permeability surface (PS) in patients with diabetes confirms pulmonary microcirculation damage in these patients.