How Unavoidable Are Analytical Treatment Interruptions in HIV Cure–Related Studies?. (2nd July 2019)

• Record Type: Journal Article
• Authors: Margolis, David M; Deeks, Steven G
• Is Part Of: Journal of infectious diseases. Volume 220(2019)Supplement 1
• Page Start: S24
• Page End: S26
• Publication Date: 2019-07-02
• Subjects: Analytical treatment interruption -- antiretroviral therapy -- viral outgrowth assay; Communicable diseases -- Periodicals; Diseases -- Causes and theories of causation -- Periodicals; Medicine -- Periodicals; Communicable Diseases -- Periodicals; Electronic journals; 616.9
• DOI: 10.1093/infdis/jiz222
• Languages: English
• ISSNs: 0022-1899

Abstract

Abstract: In this discussion, 2 established researchers and clinical trialists debate their opposing views on the utility, benefits, and risks of the use of analytical interruption of antiretroviral therapy as a clinical trial end point and outcome measure in human studies seeking to induce remission of or eradicate human immunodeficiency virus infection.