Can inpatient multidisciplinary rehabilitation improve health-related quality of life in MS patients on the long term – The Danish MS Hospitals Rehabilitation Study. (December 2020)

• Record Type: Journal Article
• Authors: Boesen, Finn; Nørgaard, Michael; Skjerbæk, Anders Guldhammer; Rasmussen, Peter Vestergaard; Petersen, Thor; Løvendahl, Brita; Trénel, Philipp
• Is Part Of: Multiple sclerosis. Volume 26:Number 14(2020)
• Page Start: 1953
• Page End: 1957
• Publication Date: 2020-12
• Subjects: Health-related quality of life -- long term -- multiple sclerosis -- multidisciplinary rehabilitation; Central nervous system -- Diseases -- Periodicals; Myelin sheath -- Diseases -- Periodicals; Inflammation -- Periodicals; Multiple sclerosis -- Periodicals; Central Nervous System Diseases -- Periodicals; Demyelinating Diseases -- Periodicals; Inflammation -- Periodicals; Multiple Sclerosis -- Periodicals; Système nerveux central -- Maladies -- Périodiques; Gaine de myéline -- Maladies -- Périodiques; Inflammation (Pathologie) -- Périodiques; Sclérose en plaques -- Périodiques; Electronic journals; 616.834005
• DOI: 10.1177/1352458519884244
• Languages: English
• ISSNs: 1352-4585

Abstract

Background: Inpatient multidisciplinary rehabilitation (MDR) can improve health-related quality of life (HRQoL) in multiple sclerosis (MS) patients. However, the evidence of a long-term benefit is limited. Objectives: To investigate the long-term effectiveness of inpatient MDR on HRQoL in MS patients. Methods: We conducted a randomized controlled partial crossover trial with 427 MS patients. Results: Statistical significant long-term improvements in HRQoL were found in three of the six outcome measures at 12-month follow-up. Three in four suggested minimal clinically important differences (MCIDs) were unmet. Conclusion: These results indicate that the administration of inpatient MDR may lead to long-lasting improvements in HRQoL in MS patients.