A highly selective and sensitive photoinduced electron transfer (PET) based HOCl fluorescent probe in water and its endogenous imaging in living cells. Issue 51 (3rd June 2016)

• Record Type: Journal Article
• Authors: Liang, Lijuan; Liu, Chang; Jiao, Xiaojie; Zhao, Liancheng; Zeng, Xianshun
• Is Part Of: Chemical communications. Volume 52:Issue 51(2016)
• Page Start: 7982
• Page End: 7985
• Publication Date: 2016-06-03
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c6cc02603f
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A probe based on the phenothiazine–acridine orange conjugate (Ptz–AO) has been designed and synthesized for the sensitive and selective detection of HOCl. Abstract : A probe based on the phenothiazine–acridine orange conjugate (Ptz–AO) has been designed and synthesized for the sensitive and selective detection of HOCl. Ptz–AO has excellent properties, including pH-independence of fluorescence, high resistance to photobleaching, and response in real time. The value of Ptz–AO was confirmed by exogenous, endogenous and the real-time imaging of HOCl in vitro using a fluorescence microscope.