A palladium-catalyzed intramolecular carbonylative annulation reaction for the synthesis of 4, 5-fused tricyclic 2-quinolones. Issue 49 (26th May 2016)
- Record Type:
- Journal Article
- Title:
- A palladium-catalyzed intramolecular carbonylative annulation reaction for the synthesis of 4, 5-fused tricyclic 2-quinolones. Issue 49 (26th May 2016)
- Main Title:
- A palladium-catalyzed intramolecular carbonylative annulation reaction for the synthesis of 4, 5-fused tricyclic 2-quinolones
- Authors:
- Zhang, Xiwu
Liu, Haichao
Jia, Yanxing - Abstract:
- Abstract : A new method for the synthesis of 4, 5-fused tricyclic 2-quinolones via a palladium-catalyzed intramolecular carbonylative annulation reaction is described. Abstract : A concise and efficient synthetic route to 4, 5-fused tricyclic 2-quinolones through the palladium-catalyzed carbonylative annulation of alkyne-tethered N -substituted o -iodoanilines has been developed. This reaction proceeds smoothly under mild reaction conditions and exhibits exceptional tolerance to a variety of functional groups. It has been successfully applied to the efficient synthesis of BI 224436, an HIV integrase inhibitor.
- Is Part Of:
- Chemical communications. Volume 52:Issue 49(2016)
- Journal:
- Chemical communications
- Issue:
- Volume 52:Issue 49(2016)
- Issue Display:
- Volume 52, Issue 49 (2016)
- Year:
- 2016
- Volume:
- 52
- Issue:
- 49
- Issue Sort Value:
- 2016-0052-0049-0000
- Page Start:
- 7665
- Page End:
- 7667
- Publication Date:
- 2016-05-26
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c6cc02600a ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 14473.xml