The Concise Guide to PHARMACOLOGY 2015/16: Overview. (December 2015)

• Record Type: Journal Article
• Authors: Alexander, Stephen PH; Kelly, Eamonn; Marrion, Neil; Peters, John A; Benson, Helen E; Faccenda, Elena; Pawson, Adam J; Sharman, Joanna L; Southan, Christopher; Buneman, O Peter; Catterall, William A; Cidlowski, John A; Davenport, Anthony P; Fabbro, Doriano; Fan, Grace; McGrath, John C; Spedding, Michael; Davies, Jamie A
• Other Names: Aldrich R investigator.; Attali B investigator.; Bäck Ml investigator.; Barnes NM investigator.; Bathgate R investigator.; Beart PM investigator.; Becirovic E investigator.; Biel M investigator.; Birdsall NJ investigator.; Boison D investigator.; Bräuner‐Osborne H investigator.; Bröer S investigator.; Bryant C investigator.; Burnstock G investigator.; Burris T investigator.; Cain D investigator.; Calo G investigator.; Chan SL investigator.; Chandy KG investigator.; Chiang N investigator.; Christakos S investigator.; Christopoulos A investigator.; Chun JJ investigator.; Chung J‐J investigator.; Clapham DE investigator.; Connor MA investigator.; Coons L investigator.; Cox HM investigator.; Dautzenberg FM investigator.; Dent G investigator.; Douglas SD investigator.; Dubocovich ML investigator.; Edwards DP investigator.; Farndale R investigator.; Fong TM investigator.; Forrest D investigator.; Fowler CJ investigator.; Fuller P investigator.; Gainetdinov RR investigator.; Gershengorn MA investigator.; Goldin A investigator.; Goldstein SAN investigator.; Grimm SL investigator.; Grissmer S investigator.; Gundlach AL investigator.; Hagenbuch B investigator.; Hammond JR investigator.; Hancox JC investigator.; Hartig S investigator.; Hauger RL investigator.; Hay DL investigator.; Hébert T investigator.; Hollenberg AN investigator.; Holliday ND investigator.; Hoyer D investigator.; Ijzerman AP investigator.; Inui KI investigator.; Ishii S investigator.; Jacobson KA investigator.; Jan LY investigator.; Jarvis GE investigator.; Jensen R investigator.; Jetten A investigator.; Jockers R investigator.; Kaczmarek LK investigator.; Kanai Y investigator.; Kang HS investigator.; Karnik S investigator.; Kerr ID investigator.; Korach KS investigator.; Lange CA investigator.; Larhammar D investigator.; Leeb‐Lundberg F investigator.; Leurs R investigator.; Lolait SJ investigator.; Macewan D investigator.; Maguire JJ investigator.; May JM investigator.; Mazella J investigator.; Mcardle CA investigator.; Mcdonnell DP investigator.; Michel MC investigator.; Miller LJ investigator.; Mitolo V investigator.; Monie T investigator.; Monk PN investigator.; Mouillac B investigator.; Murphy PM investigator.; Nahon J‐L investigator.; Nerbonne J investigator.; Nichols CG investigator.; Norel X investigator.; Oakley R investigator.; Offermanns S investigator.; Palmer LG investigator.; Panaro MA investigator.; Perez‐Reyes E investigator.; Pertwee RG investigator.; Pike JW investigator.; Pin JP investigator.; Pintor S investigator.; Plant LD investigator.; Poyner DR investigator.; Prossnitz ER investigator.; Pyne S investigator.; Ren D investigator.; Richer JK investigator.; Rondard P investigator.; Ross RA investigator.; Sackin H investigator.; Safi R investigator.; Sanguinetti MC investigator.; Sartorius CA investigator.; Segaloff DL investigator.; Sladek FM investigator.; Stewart G investigator.; Stoddart LA investigator.; Striessnig J investigator.; Summers RJ investigator.; Takeda Y investigator.; Tetel M investigator.; Toll L investigator.; Trimmer JS investigator.; Tsai M‐J investigator.; Tsai SY investigator.; Tucker S investigator.; Usdin TB investigator.; Vilargada J‐P investigator.; Vore M investigator.; Ward DT investigator.; Waxman SG investigator.; Webb P investigator.; Wei AD investigator.; Weigel N investigator.; Willars GB investigator.; Winrow C investigator.; Wong SS investigator.; Wulff H investigator.; Ye RD investigator.; Young M investigator.; Zajac J‐M investigator.;
• Is Part Of: British journal of pharmacology. Volume 172:Number 24(2015:Dec.)
• Page Start: 5729
• Page End: 5743
• Publication Date: 2015-12
• Subjects: Pharmacology -- Periodicals; Chemotherapy -- Periodicals; Drug Therapy -- Periodicals; Pharmacology -- Periodicals; 615.1
• DOI: 10.1111/bph.13347
• Languages: English
• ISSNs: 0007-1188

Abstract

Abstract : The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org ), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13347/full . This compilation of the major pharmacological targets is divided into eight areas of focus: G protein‐coupled receptors, ligand‐gated ion channels, voltage‐gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC‐IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR‐DB and GRAC and provides a permanent, citable, point‐in‐time record that will survive database updates.