Large‐Scale Nanoelectrode Arrays to Monitor the Dopaminergic Differentiation of Human Neural Stem Cells. (21st September 2015)

• Record Type: Journal Article
• Authors: Kim, Tae‐Hyung; Yea, Cheol‐Heon; Chueng, Sy‐Tsong Dean; Yin, Perry To‐Tien; Conley, Brian; Dardir, Kholud; Pak, Yusin; Jung, Gun Young; Choi, Jeong‐Woo; Lee, Ki‐Bum
• Is Part Of: Advanced materials. Volume 27:Number 41(2015)
• Page Start: 6356
• Page End: 6362
• Publication Date: 2015-09-21
• Subjects: dopaminergic differentiation -- electrochemical detection -- large‐scale nanopatterning -- nanoelectrode arrays -- neural stem cells; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201502489
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : A novel cell‐based biosensing platform is developed using a combination of sequential laser interference lithography and electrochemical deposition methods. This enables the sensitive discrimination of dopaminergic cells from other types of neural cells in a completely nondestructive manner. This platform and detection strategy may become an effective noninvasive in situ monitoring tool that can be used to determine stem cell fate for various regenerative applications.