Lisch nodules and iris mammillations in two siblings with familial legius syndrome. Issue 10 (1st September 2020)

• Record Type: Journal Article
• Authors: Bixel, Kaitlyn D.; Cano, Miguel J.; Johnson, Damon M.; Gomez, Benjamin; Lobsinger, Laura V.; Valentin, Frank E.; Hsieh, David T.; Rohena, Luis O.
• Is Part Of: Clinical case reports. Volume 8:Issue 10(2020)
• Page Start: 1867
• Page End: 1871
• Publication Date: 2020-09-01
• Subjects: café‐au‐lait macules -- legius syndrome -- lisch nodules -- neurofibromatosis type 1 -- neurofibromatosis type 1‐like syndrome -- NF1 -- SPRED1; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.2861
• Languages: English
• ISSNs: 2050-0904

Abstract

Abstract: Legius syndrome is characterized by numerous café‐au‐lait macules and intertriginous freckling, but typically lacks the distinctive tumor manifestations of neurofibromatosis type 1. We report two siblings with Legius syndrome and Lisch nodules illustrating the importance of eye surveillance in these patients. Abstract : Legius syndrome is characterized by numerous café‐au‐lait macules and intertriginous freckling, but typically lacks the distinctive tumor manifestations of neurofibromatosis type 1. We report two siblings with Legius syndrome and Lisch nodules illustrating the importance of eye surveillance in these patients.