Organic synthesis of high added value molecules with MOF catalysts. Issue 40 (1st October 2020)

• Record Type: Journal Article
• Authors: Martín, Nuria; Cirujano, Francisco G.
• Is Part Of: Organic & biomolecular chemistry. Volume 18:Issue 40(2020)
• Page Start: 8058
• Page End: 8073
• Publication Date: 2020-10-01
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/d0ob01571g
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : Recent examples of organic synthesis of fine chemicals and pharmaceuticals in confined spaces of MOFs are highlighted and compared with silica-based ordered porous solids, such as zeolites or mesoporous (organo)silica. Abstract : Recent examples of organic synthesis of fine chemicals and pharmaceuticals in confined spaces of MOFs are highlighted and compared with silica-based ordered porous solids, such as zeolites or mesoporous (organo)silica. These heterogeneous catalysts offer the possibility of stabilizing the desired transition states and/or intermediates during organic transformations of functional groups and (C–C/C–N) bond forming steps towards the desired functional high added value molecular scaffolds. A short introduction on zeolites, mesoporous silica and metal–organic frameworks is followed by relevant applications in which confined active sites in the pores promote single or multi-step organic synthesis of industrially relevant molecules. A critical discussion on the catalytic performances of the different types of hybrid inorganic–organic catalysts in the synthesis of O- and N-containing acyclic and heterocyclic molecules has been presented.