Recurrent versus first cervical artery dissection – a retrospective study of clinical and vascular characteristics. (22nd July 2020)

• Record Type: Journal Article
• Authors: Kloss, M.; Kalashnikova, L.; Dobrynina, L.; Traenka, C.; Engelter, S. T.; Metso, T. M.; Tatlisumak, T.; Urbanek, C.; Grau, A.; Kellert, L.; Brandt, T.; Wieker, C. M.; Grond‐Ginsbach, C.; Pezzini, A.
• Is Part Of: European journal of neurology. Volume 27:Number 11(2020)
• Page Start: 2185
• Page End: 2190
• Publication Date: 2020-07-22
• Subjects: arterial dissection -- epidemiology -- cerebrovascular diseases and cerebral circulation -- cerebral infarction; Neurology -- Periodicals; Nervous system -- Diseases -- Periodicals; 616.8
• DOI: 10.1111/ene.14417
• Languages: English
• ISSNs: 1351-5101

Abstract

Abstract : Background and purpose: Most recurrent cervical artery dissection (CeAD) events occur shortly after the acute first CeAD. This study compared the characteristics of recurrent and first CeAD events and searched for associations between subsequent events of an individual person. Methods: Cervical artery dissection patients with a new CeAD event occurring during a 3–6 month follow‐up were retrospectively selected in seven specialized stroke centers. Clinical and vascular characteristics of the initial and the recurrent CeADs were compared. Results: The study sample included 76 patients. Recurrent CeADs were occlusive in one (1.3%) patient, caused cerebral ischaemia in 13 (17.1%) and were asymptomatic in 39 (51.3%) patients, compared to 29 (38.2%) occlusive, 42 (55.3%) ischaemic and no asymptomatic first CeAD events. In 52 (68.4%) patients, recurrent dissections affected both internal carotid arteries or both vertebral arteries, whilst 24 (31.6%) patients had subsequent dissections in both types of artery. Twelve (28.6%) of 42 patients with an ischaemic first dissection had ischaemic symptoms due to the recurrent CeADs, too. However, only one (1.3%) of 34 patients with a non‐ischaemic first CeAD suffered ischaemia upon recurrence. Conclusion: Recurrent CeAD typically affects the same site of artery. It causes ischaemic events less often than the first CeAD. The risk that patients who presented with solely non‐ischaemic symptoms of a first CeAD will have ischaemic symptoms in the case of a recurrent CeAD seems very small.