A Japanese case of COVID‐19: An autopsy report. Issue 10 (13th August 2020)
- Record Type:
- Journal Article
- Title:
- A Japanese case of COVID‐19: An autopsy report. Issue 10 (13th August 2020)
- Main Title:
- A Japanese case of COVID‐19: An autopsy report
- Authors:
- Okudela, Koji
Hayashi, Hiroyuki
Yoshimura, Yukihiro
Sasaki, Hiroaki
Horiuchi, Hiroshi
Miyata, Nobuyuki
Tachikawa, Natsuo
Tsuchiya, Yuki
Mitsui, Hideaki
Ohashi, Kenichi - Abstract:
- Abstract : A 93‐year‐old woman was admitted with a 10‐day history of cough and prostration. Thoracic computed tomography revealed extensive ground‐glass opacities in both the lungs. The polymerase chain reaction test of sputum for severe acute respiratory syndrome‐coronavirus‐2 (SARS‐CoV‐2) was positive. She was treated with antiviral agents and steroid pulse therapy. However, her oxygen saturation gradually declined, and she died 10 days after hospitalization. The most important autopsy finding was fuzzily segmented diffuse alveolar damage (DAD) that expanded from the subpleural to the medial area. No remarkable changes were observed in organs other than the lungs. Therefore, pneumocytes were suggested as the primary target for SARS‐CoV‐2, which might explain why coronavirus infectious disease‐19 is a serious condition. Thus, early treatment is essential to prevent viral replication from reaching a level that triggers DAD.
- Is Part Of:
- Pathology international. Volume 70:Issue 10(2020)
- Journal:
- Pathology international
- Issue:
- Volume 70:Issue 10(2020)
- Issue Display:
- Volume 70, Issue 10 (2020)
- Year:
- 2020
- Volume:
- 70
- Issue:
- 10
- Issue Sort Value:
- 2020-0070-0010-0000
- Page Start:
- 820
- Page End:
- 824
- Publication Date:
- 2020-08-13
- Subjects:
- COVID‐19 -- diffuse alveolar damage -- Japanese case
Pathology -- Periodicals
616.07 - Journal URLs:
- http://www.blackwell-synergy.com/member/institutions/issuelist.asp?journal=pin ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1111/pin.13002 ↗
- Languages:
- English
- ISSNs:
- 1320-5463
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 6412.823000
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British Library HMNTS - ELD Digital store - Ingest File:
- 14431.xml