Efficient viscosity contrast calculation for blood flow simulations using the lattice Boltzmann method. (15th April 2020)

• Record Type: Journal Article
• Authors: Lehmann, Moritz; Müller, Sebastian Johannes; Gekle, Stephan
• Is Part Of: International journal for numerical methods in fluids. Volume 92:Number 11(2020)
• Page Start: 1463
• Page End: 1477
• Publication Date: 2020-04-15
• Subjects: lattice Boltzmann Method -- immersed boundary -- viscosity contrast -- red blood cell -- microchannel; Fluid dynamics -- Mathematics -- Periodicals; 532
• DOI: 10.1002/fld.4835
• Languages: English
• ISSNs: 0271-2091

Abstract

Summary: The lattice Boltzmann method (LBM) combined with the immersed boundary method is a common tool to simulate the movement of red blood cel ls (RBCs) through blood vessels. With very few exceptions, such simulations neglect the difference in viscosities between the hemoglobin solution inside the cells and the blood plasma outside, although it is well known that this viscosity contrast can severely affect cell deformation. While it is easy to change the local viscosity in LBM, the challenge is to distinguish whether a given lattice point is inside or outside the RBC at each time step. Here, we present a fast algorithm to solve this issue by tracking the membrane motion and computing the scalar product between the local surface normal and the distance vector between the closest LBM lattice point and the surface. This approach is much faster than, for example, the ray‐casting method. With the domain tracking applied, we investigate the shape transition of a RBC in a microchannel for different viscosity contrast and validate our method by comparing with boundary‐integral simulations. Abstract : We use the immersed‐boundary lattice Boltzmann method to simulate the movement of red blood cells (RBCs) through blood vessels. The viscosity contrast between the hemoglobin solution inside the cells and the blood plasma outside is known to severely affect cell deformation, but due its high computational cost has often been ignored. We present a fast algorithm for tracking which lattice points are inside or outside the RBC at each time step.