Efficient summary statistics for detecting lineage fusion from phylogeographic datasets. (22nd July 2020)

• Record Type: Journal Article
• Authors: Garrick, Ryan C.; Hyseni, Chaz; Arantes, Ísis C.
• Is Part Of: Journal of biogeography. Volume 47:Number 10(2020:Oct.)
• Page Start: 2129
• Page End: 2140
• Publication Date: 2020-07-22
• Subjects: demographic history -- ephemeral lineage -- fission‐fusion -- lineage fusion -- neutrality test -- nucleotide diversity -- phylogeography -- population merging -- secondary contact; Biogeography -- Periodicals; 578.09
• DOI: 10.1111/jbi.13932
• Languages: English
• ISSNs: 0305-0270

Abstract

Abstract: Aim: Lineage fusion (merging of two or more populations of a species resulting in a single panmictic group) is a special case of secondary contact. It has the potential to counteract diversification and speciation, or to facilitate it through creation of novel genotypes. Understanding the prevalence of lineage fusion in nature requires reliable detection of it, such that efficient summary statistics are needed. Here, we report on simulations that characterized the initial intensity and subsequent decay of signatures of past fusion for 17 summary statistics applicable to DNA sequence haplotype data. Location: Global. Taxa: Diploid out‐crossing species. Methods: We considered a range of scenarios that could reveal the impacts of different combinations of read length versus number of loci (arrangement of DNA sequence data), and whether or not pre‐fusion populations experienced bottlenecks coinciding with their divergence (historical context of fusion). Post‐fusion gene pools were sampled along 10 successive time points representing increasing lag times following merging of sister populations, and summary statistic values were recalculated at each. Results: Many summary statistics were able to detect signatures of complete merging of populations after a sampling lag time of 1.5 N e generations, but the most informative ones included two neutrality tests and four diversity metrics, with ZnS (a linkage disequilibrium‐based neutrality test) being particularly powerful. Correlation was relatively low among the two neutrality tests and two of the diversity metrics. There were clear benefits of many short (200‐bp × 200) loci over a handful of long (4‐kb × 10) loci. Also, only the latter genetic dataset type showed impacts of bottlenecks during divergence upon the number of informative summary statistics. Main conclusions: This work contributes to identifying cases of lineage fusion, and advances phylogeography by enabling more nuanced reconstructions of how individual species, or multiple members of an ecological community, responded to past environmental change.