A novel insight to screen the optimal spray-drying protectants and parameters for manufacturing lactic acid bacteria preparations. Issue 14 (1st October 2020)

• Record Type: Journal Article
• Authors: Zhang, Zhuo; Peng, Sen; Sun, Xiaoqi; Jie, Yu; Zhao, Hongfei; Zhu, Baoqing; Dziugan, Piotr; Zhang, Bolin
• Is Part Of: Drying technology. Volume 38:Issue 14(2020)
• Page Start: 1843
• Page End: 1856
• Publication Date: 2020-10-01
• Subjects: Spray drying -- lactic acid bacteria -- protectants -- β-galactosidase -- liposome; Drying -- Periodicals; Desiccation; 660.28426
• DOI: 10.1080/07373937.2019.1674323
• Languages: English
• ISSNs: 0737-3937

Abstract

Abstract: This study constructed a β-galactosidase (β-gal) liposome model instead of bacterial cells to optimize spray-drying protectants and parameters. The screened protectant combination consisted of 35 g/L monosodium glutamate, 50 g/L sucrose, and 35 g/L maltodextrin. The optimal parameters for spray drying were 130 °C inlet air temperature, 7.5 mL/min feed flow rate, and 150 mL optimal protectant combination. The viability of the five lactic acid bacteria strains spray-dried with the optimized protectant and parameters was over 50%. Lactobacillus helveticus strain LH-9's mechanism of resistance to spray-dry treatment was investigated in the presence of the optimal protectant combination.