Postendodontic Pain after Pulpotomy or Root Canal Treatment in Mature Teeth with Carious Pulp Exposure: A Multicenter Randomized Controlled Trial. (30th June 2020)

• Record Type: Journal Article
• Authors: Eghbal, Mohammad Jafar; Haeri, Ali; Shahravan, Arash; Kazemi, Ali; Moazami, Fariborz; Mozayeni, Mohammad Ali; Saberi, Eshaghali; Samiei, Mohammad; Vatanpour, Mehdi; Akbarzade Baghban, Alireza; Fazlyab, Mahta; Parhizkar, Ardavan; Ahmadi, Mahboobe; Akbarian Rad, Nazila; Bijari, Shima; Bineshmarvasti, Delaram; Davoudi, Paria; Dehghan, Roya; Dehghani, Mandana; Ebrahimi, Habibollah; Emami, Nafiseh; Farajian, Nafiseh; Fereidooni, Rahim; Ghobadi, Gelareh; Ghodrati, Mostafa; Gohari, Atefeh; Hashemi, Azadeh; Hosseini, Mohammadreza; Karami, Elham; Kheirabadi, Nasir; Kozegari, Sepideh; Labaf Ghasemi, Hadi; Majidi, Alireza; Malekzadeh, Parastu; Mehrabi, Vahid; Mohammadi, Mehrnush; Moradi Eslami, Leila; Noghani, Atefeh; Omatali, Negin; Pourhatami, Negar; Rahbani Nobar, Behnam; Rahmani, Saeid; Shafaq, Parviz; Soofiabadi, Sara; Teimoori, Somaye; Vatandoost, Farzaneh; Asgary, Saeed;
• Other Names: Kasai Shinya Academic Editor.
• Is Part Of: Pain research and management. Volume 2020(2020)
• Publication Date: 2020-06-30
• Subjects: Pain -- Periodicals; Pain -- Treatment -- Periodicals; 616.0472
• DOI: 10.1155/2020/5853412
• Languages: English
• ISSNs: 1203-6765

Abstract

Abstract : This equivalence, randomized, clinical trial aimed to compare the postoperative pain of root canal therapy (RCT) with pulpotomy with mineral trioxide aggregate (PMTA) or calcium-enriched mixture (PCEM) in permanent mature teeth. In seven academic centers, 550 cariously exposed pulps were included and randomly allocated into PMTA ( n = 188), PCEM ( n = 194), or RCT ( n = 168) arms. Preoperative "Pain Intensity" (PI) on Numerical Rating Scale and postoperative PIs until day 7 were recorded. Patients' demographic and pre-/intra-/postoperative factors/conditions were recorded/analysed. The arms were homogeneous in terms of demographics. The mean preoperative PIs were similar (P = 0.998 ), the mean sum PIs recorded during 10 postoperative intervals were comparable (P = 0.939 ), and the trend/changes in pain relief were parallel (P = 0.821 ) in all study arms. The incidences of preoperative moderate-severe pain in RCT, PMTA, and PCEM arms were 56.5%, 55.7%, and 56.7%, which after 24 hours considerably decreased to 13.1%, 10.6%, and 12.9%, respectively (P = 0.578 ). The time span of endodontic procedures was statistically different; RCT = 69.73, PMTA = 35.37, and PCEM = 33.62 minutes (P < 0.001 ). Patients with greater preoperative pain, symptomatic apical periodontitis, or presence of PDL widening suffered more pain (P = 0.002, 0.035, and 0.023, resp.); however, other pre-/intra-/postoperative factors/conditions were comparable. Pulpotomy with MTA/CEM and RCT demonstrate comparable and effective postoperative pain relief.