A Rare Case of Light Chain Amyloidosis of the Gastrointestinal Tract. (30th June 2020)

• Record Type: Journal Article
• Authors: Dvir, Kathrin; Galarza-Fortuna, Gliceida M.; Willet, Anna; Febres-Aldana, Christopher; Cortez, Nathaly; Rapaka, Samuel; Coombs, Andre; Goldberg, Robert; Schwartz, Michael; Ben-David, Kfir
• Other Names: Mantas Dimitrios Academic Editor.
• Is Part Of: Case reports in surgery. Volume 2020(2020)
• Publication Date: 2020-06-30
• Subjects: Surgery -- Periodicals; Surgery -- Case studies -- Periodicals; Surgical Procedures, Operative; General Surgery; Surgery; Electronic journals; Periodicals; Case studies; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 617
• DOI: 10.1155/2020/1921805
• Languages: English
• ISSNs: 2090-6900

Abstract

Abstract : A 65-year-old Hispanic female presented with a one-year history of anorexia, nausea, early satiety, epigastric discomfort, and a 20 kg weight loss. Computed tomography (CT) demonstrated heterogeneous liver parenchyma. Upper endoscopy revealed large, fungating, infiltrative mass at the lesser gastric curvature incisura, highly suspicious of gastric tumor; however, initial biopsy of the gastric mass was equivocal and an exploratory laparoscopy was performed. Repeated intraoperative biopsies of the gastric mass and of liver parenchyma demonstrated diffuse hyalinized stroma consistent with amyloid deposition, and a bone marrow biopsy confirmed the diagnosis of primary light chain (AL) amyloidosis.