Benign Histiocyte-Rich Pseudotumor Developing Postchemotherapy and Mimicking Residual Disease. (2nd July 2020)

• Record Type: Journal Article
• Authors: Singh, Amrit P.; Murray, Glenn P.; Pandey, Soumya
• Other Names: Batinac Tanja Academic Editor.
• Is Part Of: Case reports in pathology. Volume 2020(2020)
• Publication Date: 2020-07-02
• Subjects: Pathology -- Periodicals; Pathology; Pathology; Electronic journals; Periodicals; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 616.07
• DOI: 10.1155/2020/4674103
• Languages: English
• ISSNs: 2090-6781

Abstract

Abstract : Histiocyte-rich pseudotumors (HRPT) developing postchemoradiation therapy are a florid response to treatment and reparative change. Although these are benign processes, clinically and radiologically, these may mimic recurrent/relapsed disease. We describe a case of an adult male with history of diffuse large B-cell lymphoma (DLBCL), status postchemoradiation therapy, who developed HRPT at the site of original involvement, mimicking relapse of disease on positron emission tomography/computed tomography (PET/CT) imaging. This is one of the few reported cases of posttreatment HRPT. This entity is important to point out the limitations of PET/CT imaging in patients with lymphomas and metastatic disease and stresses the importance of an excisional biopsy for determining relapse and the need for further treatment.