Does tumor size influence the outcome of laparoscopic distal pancreatectomy?. Issue 9 (September 2020)

• Record Type: Journal Article
• Authors: Kazaryan, Airazat M.; Solberg, Ingeborg; Aghayan, Davit L.; Sahakyan, Mushegh A.; Reiertsen, Ola; Semikov, Vasiliy I.; Shulutko, Alexander M.; Edwin, Bjørn
• Is Part Of: HPB. Volume 22:Issue 9(2020)
• Page Start: 1280
• Page End: 1287
• Publication Date: 2020-09
• Subjects: Liver -- Diseases -- Periodicals; Biliary tract -- Diseases -- Periodicals; Pancreas -- Diseases -- Periodicals; 616.362005
• DOI: 10.1016/j.hpb.2019.11.014
• Languages: English
• ISSNs: 1365-182X

Abstract

Abstract: Background: Laparoscopic distal pancreatectomy (LDP) is a safe procedure, but its role in resection of large pancreatic lesions has been questioned. Methods: Patients who underwent LDP for pancreatic solitary tumors in 1997–2017 were included in this study. The patients were divided into three groups in accordance with tumor size: <3.5 cm (group I); from 3.5 cm to 7.0 cm (group II), and ≥7 cm (group III). Results: 218, 146 and 58 patients were identified in the groups I, II and III. Median tumor size in the groups I, II and III was 20, 47 and 81.5 mm (p < 0.001). Nine procedures (2.1%) were converted including 1(0.5%), 5(3.4%) and 3(5.2%) in the groups I, II and III (p = 0.036). Median operative time was longer in the group III compared with the groups I and II – 195 vs 158 and 159 min (p = 0.005). Median blood loss did not differ. Regression analysis revealed correlation between tumor size and operative time (R = 0.103; P = 0.035) and no correlation between tumor size and blood loss (R = 0.075; P = 0.125). Hospital stay was 5 days, similar in all groups.Postoperative morbidity was similar – 38.5, 32 and 34% in the group I, II and III. Conclusion: LDP can be safely performed laparoscopically with outcomes similar to those for smaller tumors.