Value of 3Tesla MRI in the preoperative staging of mid‐low rectal cancer and its impact on clinical strategies. Issue 5 (6th August 2020)

• Record Type: Journal Article
• Authors: Xu, Liping; Zhang, Chi; Zhang, Zhaoyue; Qin, Qin; Sun, Xinchen
• Is Part Of: Asia-Pacific journal of clinical oncology. Volume 16:Issue 5(2020)
• Page Start: e216
• Page End: e222
• Publication Date: 2020-08-06
• Subjects: diagnostic accuracy -- histopathology -- magnetic resonance imaging staging -- rectal cancer; Oncology -- Pacific Area -- Periodicals; Cancer -- Treatment -- Pacific Area -- Periodicals; Cancer -- Pacific Area -- Periodicals; Cancer -- Treatment -- Periodicals; 616.9940095
• DOI: 10.1111/ajco.13368
• Languages: English
• ISSNs: 1743-7555

Abstract

Abstract: Background: To determine the diagnostic accuracy of preoperative T/N stage with magnetic resonance imaging (MRI) in lower and middle rectal cancer patients and the impacts on clinical decision‐making. Patients and methods: A total of 211 patients were recruited from October 2015 to March 2017 in this retrospective study. High‐resolution MRI was performed within 2 weeks before surgery. Histopathologic results were evaluated for the postoperative T/N stage and the diagnostic accuracy of MRI was assessed according to the postoperative histopathologic results. The accuracy, sensitivity, specificity, positive predictive value and negative predictive value were evaluated for T/N staging and κ values were used to evaluate MRI consistent analysis compared with postoperative histopathologic staging. Results: The overall MRI diagnostic accuracy was 79.62% for T1‐4 staging and 54.50% for N0‐2 staging. The κ values were 0.619 and 0.255 for T1‐4 and N0‐2 staging, respectively. The diagnostic accuracy of MRI for treatment decision‐making was 80.57%. Conclusion: MRI allows a highly accurate preoperative assessment of T stage but only a fairly accurate preoperative assessment of N stage for rectal cancer. The diagnostic accuracy of MRI for treatment decision‐making is promising, but additional studies are needed to validate these findings in a larger sample size from multiple centers.