Biochemistry, Safety, Pharmacological Activities, and Clinical Applications of Turmeric: A Mechanistic Review. (11th May 2020)

• Record Type: Journal Article
• Authors: Ahmad, Rabia Shabir; Hussain, Muhammad Bilal; Sultan, Muhammad Tauseef; Arshad, Muhammad Sajid; Waheed, Marwa; Shariati, Mohammad Ali; Plygun, Sergey; Hashempur, Mohammad Hashem
• Other Names: Calapai Gioacchino Academic Editor.
• Is Part Of: Evidence-based complementary and alternative medicine. Volume 2020(2020)
• Publication Date: 2020-05-11
• Subjects: Alternative medicine -- Periodicals; 615.505
• DOI: 10.1155/2020/7656919
• Languages: English
• ISSNs: 1741-427X

Abstract

Abstract : Turmeric ( Curcuma longa L.) is a popular natural drug, traditionally used for the treatment of a wide range of diseases. Its root, as its most popular part used for medicinal purposes, contains different types of phytochemicals and minerals. This review summarizes what is currently known on biochemistry, safety, pharmacological activities (mechanistically), and clinical applications of turmeric. In short, curcumin is considered as the fundamental constituent in ground turmeric rhizome. Turmeric possesses several biological activities including anti-inflammatory, antioxidant, anticancer, antimutagenic, antimicrobial, antiobesity, hypolipidemic, cardioprotective, and neuroprotective effects. These reported pharmacologic activities make turmeric an important option for further clinical research. Also, there is a discussion on its safety and toxicity.