Two new compounds from the heartwood of Dalbergia melanoxylon. Issue 19 (1st October 2020)

• Record Type: Journal Article
• Authors: Lin, Shuai; Liu, Rong-Hua; Ma, Guang-Qiang; Mei, Dan-Yi; Shao, Feng; Chen, Lan-Ying
• Is Part Of: Natural product research. Volume 34:Issue 19(2020)
• Page Start: 2794
• Page End: 2801
• Publication Date: 2020-10-01
• Subjects: Neoflavonoid -- benzofuran -- Dalbergia melanoxylon -- antimicrobial activity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2019.1591397
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: A new neoflavonoid, named S (+)-3′-hydroxy-4′, 2, 4, 5-tetramethoxydalbergiquinol (1 ), and a new benzofuran, named (2 S, 3 S )-5-hydroxy-6-methoxy-3-methyl-2-(4′-hydroxyphenyl)-2, 3dihydrobenzofuran (4), together with two known neoflavonoids, were isolated from the heartwood of Dalbergia melanoxylon. Their structures were elucidated by a combination of spectroscopic methods and comparison with the literature. Compounds 1–4 were evaluated for inhibitory activity against Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 6538, Salmonella enteri CMCC 50041 and Candida albicans ATCC 289065, which all exhibited inactive or weak activity. Graphical Abstract: