Determination of fluoroquinolones in foods using ionic liquid modified Fe3O4/MWCNTs as the adsorbent for magnetic solid phase extraction coupled with HPLC. Issue 36 (28th August 2020)

• Record Type: Journal Article
• Authors: Zhang, Meng; Chen, Jie; Zhao, Faqiong; Zeng, Baizhao
• Is Part Of: Analytical methods. Volume 12:Issue 36(2020)
• Page Start: 4457
• Page End: 4465
• Publication Date: 2020-08-28
• Subjects: Chemistry, Analytic -- Periodicals; Analytical biochemistry -- Periodicals; Chemical laboratories -- Standards -- Periodicals; 543.1905
• DOI: 10.1039/d0ay01045f
• Languages: English
• ISSNs: 1759-9660

Abstract

Abstract : The synthesized material (Fe3 O4 /MWCNTs/IL) exhibited excellent extraction capability and the proposed detection method for FQs was simple, convenient and sensitive. Abstract : In this work, a simple and sensitive method based on Fe3 O4 /multi-walled carbon nanotubes/ionic liquid (Fe3 O4 /MWCNTs/IL) as the adsorbent for magnetic solid phase extraction coupled with high performance liquid chromatography was developed for the determination of trace fluoroquinolones in foods. After a simple one-pot solvothermal synthesis, Fe3 O4 /MWCNTs were further modified with an amine-terminated ionic liquid to enhance their dispersibility and extraction capacity. The morphology, structure and magnetic properties of the composite adsorbent were characterized by transmission electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, X-ray diffraction spectrometry and vibrating-sample magnetometry. Under the optimized extraction and detection conditions, the studied fluoroquinolones were enriched effectively and separated well and their UV signals were linear to their concentrations in the range of 4–1000 ng mL −1, with correlation coefficients ranging from 0.9958 to 0.9990. The enrichment factors were 29.1–43.9 fold and the limits of detection were 0.33–0.78 ng mL −1 . The spiked recoveries were 85.4–105.9% for milk and 85.2–103.7% for pork samples, with relative standard deviations of 0.8–5.7%. The developed method provided a fast, sensitive and reliable determination platform for fluoroquinolones in complex real samples.