An amplified electrochemical sensor employing a polymeric film and graphene quantum dots/multiwall carbon nanotubes in a deep eutectic solvent for sensitive analysis of paracetamol and 4-aminophenol. (8th September 2020)

• Record Type: Journal Article
• Authors: Arab, Nastaran; Fotouhi, Lida; Salis, Andrea; Dorraji, Parisa Seyed
• Is Part Of: New journal of chemistry. Volume 44:Number 36(2020)
• Page Start: 15742
• Page End: 15751
• Publication Date: 2020-09-08
• Subjects: Chemistry -- Periodicals; Chimie -- Périodiques; 540
• DOI: 10.1039/d0nj03371e
• Languages: English
• ISSNs: 1144-0546

Abstract

Abstract : Herein, a nanocomposite consisting of graphene quantum dots, a deep eutectic solvent and carboxyl functionalized multiwall carbon nanotubes (GQDs + DES + MWCNTs-COOH) was prepared. Abstract : Herein, a nanocomposite consisting of graphene quantum dots, a deep eutectic solvent and carboxyl functionalized multiwall carbon nanotubes (GQDs + DES + MWCNTs-COOH) was prepared. After electropolymerization of l -arginine on the surface of a glassy carbon electrode modified with the GQDs + DES + MWCNTs-COOH nanocomposite, an electrochemical sensor was fabricated. The morphology of the GQDs + DES + MWCNTs-COOH/PARG surface was characterized via field emission electron microscopy. The sensor allowed excellent performance to be obtained for the analytical monitoring of paracetamol and its metabolite 4-aminophenol. Under the optimal conditions, the prepared electrochemical sensor exhibited wide linear dynamic ranges from 0.030 to 110 μmol L −1 and 0.050 to 100 μmol L −1 for paracetamol and 4-aminophenol, respectively. Moreover, the detection limits were 0.010 μmol L −1 and 0.017 μmol L −1, for paracetamol and 4-aminophenol, respectively. The practical applicability of the constructed sensor was explored by the determination of both compounds in human fluid samples and acceptable results were obtained.