Fabrication of self‐functionalized polymeric surfaces and their application in electrochemical acetaminophen detection. Issue 48 (2nd July 2020)

• Record Type: Journal Article
• Authors: Kuralay, Filiz; Çağlayan, Tahsin; İlhan, Hasan; Dumangöz, Mehmet; Sönmez Çelebi, Mutlu
• Is Part Of: Journal of applied polymer science. Volume 137:Issue 48(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-07-02
• Subjects: conducting polymers -- copolymers -- electrochemistry -- sensors and actuators; Polymers -- Periodicals; Polymerization -- Periodicals; 668.9
• DOI: 10.1002/app.49572
• Languages: English
• ISSNs: 0021-8995

Abstract

Abstract: Conducting polymer coatings have offered functionalized surfaces having good electrical, mechanical, and physical properties. In this work, electrochemical preparation and characterization of polypyrrole/polypyrrole‐3‐carboxylic acid (PPy/PPa) copolymer onto single‐use pencil graphite electrodes (PGEs) were described and detailed. Then, the application of these electrodes was demonstrated for the detection a commonly used analgesic, acetaminophen (AC) (paracetamol). Copolymer was deposited onto PGEs using cyclic voltammetry (CV) between +0.0 V and +1.0 V versus Ag/AgCl. Experimental conditions such as the effect of monomer ratios (3:1–6:1) and cyclic scans (1 cycle to 10 cycles) on electropolymerization were examined. Coated surfaces were characterized with CV and scanning electron microscopy. Electrochemical response of the electrode in AC at various pH values was evaluated. Then, AC detection was performed based on the oxidation signal of the drug at about +0.55 V versus Ag/AgCl using differential pulse voltammetry in buffer and body fluid (serum). Abstract : Polypyrrole/polypyrrole‐3‐carboxylic acid (PPy/PPa) copolymer coating on pencil graphite electrode (PGE) improved the response of the bare electrode. This copolymer coated electrode was used for acetaminophen electrochemistry and acetaminophen detection effectively. Acetaminophen detection was performed both in buffer and in serum sensitively.