Immobilized random peptide mixtures exhibit broad antimicrobial activity with high selectivity. Issue 75 (2nd September 2020)

• Record Type: Journal Article
• Authors: Cheriker, Hadar; Stern Bauer, Tal; Oren, Yuval; Nir, Shlomo; Hayouka, Zvi
• Is Part Of: Chemical communications. Volume 56:Issue 75(2020)
• Page Start: 11022
• Page End: 11025
• Publication Date: 2020-09-02
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d0cc04759g
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : In the current study, we showed that randomly-sequenced peptide mixtures (RPMs) that were immobilized on beads exhibit high and broad bactericidal activity against various pathogenic bacteria while possessing minimal hemolytic activity. Abstract : In the current study, we evaluated the antimicrobial activity of randomly-sequenced peptide mixtures (RPMs) bearing hydrophobic and cationic residues that were immobilized on beads. We showed that these beads exhibit high and broad bactericidal activity against various pathogenic bacteria while possessing minimal hemolytic activity.