Comparative Genomics Reveals Pathogenicity-Related Loci in Shewanella algae. (30th March 2020)

• Record Type: Journal Article
• Authors: Wang, Jui-Hsing; He, Guo-Cheng; Huang, Yao-Ting; Liu, Po-Yu
• Other Names: Mastroeni Pietro Academic Editor.
• Is Part Of: Canadian journal of infectious diseases & medical microbiology =. Volume 2020(2020)
• Publication Date: 2020-03-30
• Subjects: Communicable diseases -- Periodicals; Infection -- Periodicals; Communicable diseases; Infection; Communicable Diseases; Communicable Disease Control; Electronic journals; Periodicals; Fulltext; Internet Resources; Periodicals; 616.9
• DOI: 10.1155/2020/9205197
• Languages: English
• ISSNs: 1712-9532

Abstract

Abstract : Shewanella algae is an emerging marine zoonotic pathogen and accounts for considerable mortality and morbidity in compromised hosts. However, there is scarce literature related to the understanding of the genetic background of virulence determinants in S. algae . In this study, we aim to determine the occurrence of common virulence genes in S. algae using whole-genome sequence and comparative genomic analysis. Comparative genomics reveals putative-virulence genes related to bile resistance, chemotaxis, hemolysis, and motility. We detected the existence of hlyA, hlyD, and hly III involved in hemolysis. We also found chemotaxis gene cluster cheYZA operon and cheW gene. The results provide insights into the genetic basis underlying pathogenicity in S. algae .