Natural Chalcones in Chinese Materia Medica: Licorice. (16th March 2020)

• Record Type: Journal Article
• Authors: Wang, Danni; Liang, Jing; Zhang, Jing; Wang, Yuefei; Chai, Xin
• Other Names: Seidel Veronique Academic Editor.
• Is Part Of: Evidence-based complementary and alternative medicine. Volume 2020(2020)
• Publication Date: 2020-03-16
• Subjects: Alternative medicine -- Periodicals; 615.505
• DOI: 10.1155/2020/3821248
• Languages: English
• ISSNs: 1741-427X

Abstract

Abstract : Licorice is an important Chinese materia medica frequently used in clinical practice, which contains more than 20 triterpenoids and 300 flavonoids. Chalcone, one of the major classes of flavonoid, has a variety of biological activities and is widely distributed in nature. To date, about 42 chalcones have been isolated and identified from licorice. These chalcones play a pivotal role when licorice exerts its pharmacological effects. According to the research reports, these compounds have a wide range of biological activities, containing anticancer, anti-inflammatory, antimicrobial, antioxidative, antiviral, antidiabetic, antidepressive, hepatoprotective activities, and so on. This review aims to summarize structures and biological activities of chalcones from licorice. We hope that this work can provide a theoretical basis for the further studies of chalcones from licorice.