Five-Animal Frolics Exercise Improves Anxiety and Depression Outcomes in Patients with Coronary Heart Disease: A Single-Blind Randomized Controlled Trial. (7th August 2020)

• Record Type: Journal Article
• Authors: Jiang, Jun; Chi, Qingbao; Wang, Yuting; Jin, Xue; Yu, Shui
• Other Names: Zhu Mingjun Guest Editor.
• Is Part Of: Evidence-based complementary and alternative medicine. Volume 2020(2020)
• Publication Date: 2020-08-07
• Subjects: Alternative medicine -- Periodicals; 615.505
• DOI: 10.1155/2020/6937158
• Languages: English
• ISSNs: 1741-427X

Abstract

Abstract : Introduction . The patients with coronary heart disease (CHD) always have emotional implications. As the branch of traditional Chinese medicine, Five-Animal Frolics Exercise (FAE) is a popular mind-body exercise in China and shown to improve emotional wellbeing. Aim . We aimed to explore the effects of FAE on the emotional disorders of CHD patients. Methods . CHD patients were assigned into an experiment group (EG, FAE) and a control group (CG, routine nursing care). We measured serum levels of miR-124 and miR-135 and scores of the Hamilton Depression/Anxiety scale (HAMD/HAMA), Self-Rating Anxiety Scale (SAS), the Self-Rating Depression Scale (SDS), Short Form 36 Health Survey Questionnaire (SF-36), and Pittsburgh Sleep Quality Index (PSQI). Results . After a 3-month FAE intervention, serum levels of miR-124 and miR-135 and the scores of HAMD/HAMA, SAS, SDS, and PSQI in the EG group were lower than those in the CG group, while SF-36 scores in the EG group were higher than those in the CG group (p < 0.05 ). Serum levels of miR-124 and miR-135 had a strong relationship with SAS and SDS scores (p < 0.05 ). Discussion/Implications for Practice . The study suggests that FAE intervention controls anxiety and depression outcomes and improves life quality in CHD patients by affecting serum levels of miR-124 and miR-135.