Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review. (11th March 2020)

• Record Type: Journal Article
• Authors: Wanes, Peter; Nolte, David A.; Tranesh, Ghassan A.
• Other Names: Cabibi Daniela Academic Editor.
• Is Part Of: Case reports in pathology. Volume 2020(2020)
• Publication Date: 2020-03-11
• Subjects: Pathology -- Periodicals; Pathology; Pathology; Electronic journals; Periodicals; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 616.07
• DOI: 10.1155/2020/2968467
• Languages: English
• ISSNs: 2090-6781

Abstract

Abstract : Pharyngeal liposarcomas are very rare; still more rare are dedifferentiated liposarcomas in the pharynx. An 82-year-old man presented with dysphagia, voice changes, weight loss, nasal regurgitation of liquids, and coughing spells. A 3.5 cm mass was identified in the hypopharynx. The mass was biopsied and diagnosed as a benign fibroepithelial polyp. Continued symptoms and airway obstruction prompted a pharyngectomy, and the mass was then diagnosed as dedifferentiated liposarcoma. Due to infrequency and subtle histological findings, liposarcomas of the head and neck can be misdiagnosed and recur.