Cover Feature: Synergistic Interactions Are Prevalent in Catalytic Amyloids (ChemBioChem 18/2020). (19th August 2020)

• Record Type: Journal Article
• Authors: Marshall, Liam R.; Jayachandran, Megha; Lengyel‐Zhand, Zsofia; Rufo, Caroline M.; Kriews, Austin; Kim, Min‐Chul; Korendovych, Ivan V.
• Is Part Of: Chembiochem. Volume 21:Number 18(2020)
• Page Start: 2550
• Page End: 2550
• Publication Date: 2020-08-19
• Subjects: amyloids -- catalysis -- peptides -- self-assembly -- synergistic interactions; Biochemistry -- Periodicals; Molecular biology -- Periodicals; Pharmaceutical chemistry -- Periodicals; 572
• DOI: 10.1002/cbic.202000570
• Languages: English
• ISSNs: 1439-4227

Abstract

Abstract : Just like a limited set of playing cards can provide many combinations, mixtures of peptides with different amino acids can form various functional materials. Even simple binary mixtures of heptapeptides can synergistically form catalytic amyloids with high (using arginine and glutamine), moderate (using lysine and glutamate), or low (using histidine and tyrosine) hydrolytic activities. More information can be found in the communication by I. V. Korendovych et al.