DuoResp® Spiromax® adherence, satisfaction and ease of use: findings from a multi-country observational study in patients with asthma and COPD in Europe (SPRINT). (2nd October 2020)

• Record Type: Journal Article
• Authors: van der Palen, Job; Cerveri, Isa; Roche, Nicolas; Singh, Dave; Plaza, Vicente; Gonzalez, Chelo; Patino, Oliver; Scheepstra, Irma; Safioti, Guilherme; Backer, Vibeke
• Is Part Of: Journal of asthma. Volume 57:Number 10(2020)
• Page Start: 1110
• Page End: 1118
• Publication Date: 2020-10-02
• Subjects: Asthma -- COPD -- ICS/LABA -- DuoResp Spiromax -- adherence -- satisfaction; Asthma -- Periodicals; 616.238005
• DOI: 10.1080/02770903.2019.1634097
• Languages: English
• ISSNs: 0277-0903

Abstract

Abstract: Objective: Adherence and inhaler technique are often suboptimal in asthma and chronic obstructive pulmonary disease (COPD). New inhalers have been developed to improve these determinants of treatment effectiveness. We assessed treatment adherence, satisfaction, and ease of use of DuoResp ® Spiromax ® among SPRINT study participants. Methods: The Phase IV SPRINT study was conducted in 10 European countries. Asthma and COPD patients were receiving a fixed-dose combination of inhaled corticosteroid (ICS) and long-acting β2 -agonist (LABA), delivered via various inhalers including DuoResp Spiromax. DuoResp Spiromax users self-assessed adherence using the 8-item Morisky Medication Adherence Scale (MMAS-8 ® ), and ease of use and satisfaction using 10-point scales, during a single physician's office visit. Results: Of 1661 (asthma: n = 1101; COPD: n = 560) SPRINT study participants, 342 (asthma: n = 235; COPD: n = 107) received DuoResp Spiromax prior to inclusion. Overall, 72.5% of DuoResp Spiromax users reported medium or high adherence (MMAS-8 score ≥6). Mean (standard deviation [SD]) satisfaction score for DuoResp Spiromax was 8.9 (1.6). Almost all (98.8%) DuoResp Spiromax users were at least satisfied with their inhaler; 85.4% were very satisfied. Mean (SD) ease of use score for DuoResp Spiromax was 9.1 (1.3). Conclusions: Asthma and COPD patients using DuoResp Spiromax reported moderate-to-high medication adherence, were very satisfied with their inhaler and found it easy to use.