Palladium-catalyzed [4 + 3] dearomatizing cycloaddition reaction of N-iminoquinolinium ylides. Issue 18 (20th May 2020)

• Record Type: Journal Article
• Authors: Dai, Wenhao; Li, Chunpu; Liu, Yichu; Han, Xu; Li, Xingjun; Chen, Kaixian; Liu, Hong
• Is Part Of: Organic chemistry frontiers. Volume 7:Issue 18(2020)
• Page Start: 2612
• Page End: 2617
• Publication Date: 2020-05-20
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/d0qo00320d
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : An efficient approach to obtain saturated seven-membered ring containing three heteroatoms has been developed by using a palladium-catalyzed [4 + 3] dearomatizing cycloaddition. This approach features mild conditions and good functional group tolerance. Abstract : In this study, a palladium-catalyzed [4 + 3] dearomatizing cycloaddition of N -iminoquinolinium ylides has been developed for the construction of saturated seven-membered ring in good yields. This approach features mild reaction conditions and good functional group tolerance. Furthermore, gram-scale preparation and transformation were carried out, which further underscored its synthetic utility and applicability.