Multi‐Well Sensor Platform Based on a Partially Etched Structure of a Light‐Addressable Potentiometric Sensor. Issue 12 (19th December 2018)

• Record Type: Journal Article
• Authors: Truong, Hoang Anh; Werner, Carl Frederik; Miyamoto, Ko‐ichiro; Yoshinobu, Tatsuo
• Other Names: Wagner Patrick guestEditor.; Doll Theodor guestEditor.; Wagner Torsten guestEditor.; Mertig Michael guestEditor.; Schöning Michael J. guestEditor.
• Is Part Of: Physica status solidi. Volume 216:Issue 12(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-12-19
• Subjects: chemical imaging sensors -- light‐addressable potentiometric sensors -- multi‐well sensors -- spatial resolution; Solid state physics -- Periodicals; Solids -- Industrial applications -- Periodicals; 530.41
• DOI: 10.1002/pssa.201800764
• Languages: English
• ISSNs: 1862-6300

Abstract

Abstract : A multi‐well‐structured light‐addressable potentiometric sensor (LAPS) plate is developed for measuring a plurality of sample solutions on a single sensor plate. It is also capable of high‐resolution chemical imaging inside the well structure. It can be applied, for example, to quantification of metabolic activities and imaging of biological samples incubated in the well structure. A minimum pattern size of 20 µm line is visualized and a wider frequency bandwidth of up to 200 kHz for the sensor signal is obtained in the well structure, which will be suitable for recording chemical images at a high‐frame‐rate. Abstract : A multi‐well‐structured light‐addressable potentiometric sensor (LAPS) plate is developed. With multiple wells on the sensing surface, this sensor is capable of measuring a plurality of sample solutions on a single sensor plate without additional multi‐chamber structures. The application of the sensor includes quantification of metabolic activities and imaging of biological samples incubated in the well structure.