Disposable Biosensor Based on Amidase/CeO2/GNR Modified Inkjet‐printed CNT Electrodes‐droplet Based Paracetamol Detection in Biological Fluids for "Point‐of‐care" Applications. Issue 8 (22nd May 2019)

• Record Type: Journal Article
• Authors: Stanković, Dalibor M.; Ognjanović, Miloš; Jović, Milica; Cuplić, Valentina; Lesch, Andreas; Girault, Hubert H.; Gavrović Jankulović, Marija; Antić, Bratislav
• Is Part Of: Electroanalysis. Volume 31:Issue 8(2019)
• Page Start: 1517
• Page End: 1525
• Publication Date: 2019-05-22
• Subjects: acetaminophen -- amidase -- biosensor -- cerium dioxide/graphene nanoribbons composite -- inkjet-printed sensors; Electrochemical analysis -- Periodicals; Chemistry, Analytical -- Periodicals; Electrochemistry -- Periodicals; 543.4
• DOI: 10.1002/elan.201900129
• Languages: English
• ISSNs: 1040-0397

Abstract

Abstract: A disposable acetaminophen biosensor based on inkjet‐printed CNT electrodes (IJPCNT) modified with amidase/cerium dioxide@graphene nanoribbons composite was developed (ACeO2@GNR/IJPCNT). The enzyme amidase A was used for the first time as a recognition element. Inkjet‐printed CNT electrodes served as a basis for the construction of a biosensor that enables droplet detection using 5 μL sample volume. The biosensor showed high selectivity, sensitivity, a low detection limit of 0.18 μM and a wide working linear range from 1 to 100 μM. The proposed approach allows fast and reliable detection of acetaminophen in biological fluids with negligible matrix effect and remarkable reproducibility. Abstract :