Benign tremulous parkinsonism of the young-consider Parkin. (August 2019)

• Record Type: Journal Article
• Authors: Mulroy, Eoin; Balint, Bettina; Menozzi, Elisa; Latorre, Anna; Bhatia, Kailash P.
• Is Part Of: Parkinsonism & related disorders. Volume 65(2019)
• Page Start: 270
• Page End: 271
• Publication Date: 2019-08
• Subjects: Parkinson's disease -- Periodicals; Movement disorders -- Periodicals; Movement Disorders -- Periodicals; Nerve Degeneration -- Periodicals; Nervous System Diseases -- Periodicals; Parkinson Disease -- Periodicals; Tremor -- Periodicals; Parkinson, Maladie de -- Périodiques; Parkinson's disease; 616.833
• DOI: 10.1016/j.parkreldis.2019.05.027
• Languages: English
• ISSNs: 1353-8020

Abstract

Abstract: Benign tremulous parkinsonism is generally considered a disease of the elderly, characterised by dominance of tremor over other motor manifestations, and by slower disease progression. Herein, we draw attention to a different clinical syndrome, benign tremulous parkinsonism of the young, which we have observed in Parkin disease. Highlights: Parkin mutations cause recessively inherited juvenile and young-onset parkinsonism. Parkin disease is frequently misdiagnosed. Clinicians should consider Parkin disease in young tremulous individuals.