Bone Regeneration: Embryonic‐Like Mineralized Extracellular Matrix/Stem Cell Microspheroids as a Bone Graft Substitute (Adv. Healthcare Mater. 19/2018). Issue 19 (10th October 2018)

• Record Type: Journal Article
• Authors: Fu, Cuicui; Luo, Dan; Yu, Min; Jiang, Nan; Liu, Dawei; He, Danqing; Fu, Yu; Zhang, Ting; Qiao, Yiqiang; Zhou, Yanheng; Liu, Yan
• Is Part Of: Advanced healthcare materials. Volume 7:Issue 19(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-10-10
• Subjects: bone regeneration -- extracellular matrix -- mesenchymal stem cells -- microspheroids -- mineralization; Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201870076
• Languages: English
• ISSNs: 2192-2640

Abstract

Abstract : In article 1800705, Yanheng Zhou, Yan Liu, and co‐workers, fabricate embryonic‐like mineralized extracellular matrix/stem cell microspheroids (MECS), which provide a physiological microenvironment conducive to intracellular communication and osteogenesis, leading to excellent bone regeneration outcomes. This study demonstrates the feasibility of MECS transplantation as a promising scaffold‐free strategy for cell‐based bone regenerative therapy in tissue engineering.