One‐Pot Catalytic Synthesis of Aniline‐Copolymer‐Containing Reactive Aldehyde Groups Using a Laccase‐Mediator System. Issue 35 (18th September 2019)

• Record Type: Journal Article
• Authors: Khlupova, Maria; Morozova, Olga; Shumakovich, Galina; Vasil'eva, Irina; Zaitseva, Elena; Yaropolov, Alexander
• Is Part Of: ChemistrySelect. Volume 4:Issue 35(2019)
• Page Start: 10517
• Page End: 10519
• Publication Date: 2019-09-18
• Subjects: biocatalysis -- conducting polymer intermediate -- copolymerization -- laccase-mediator system -- template enzymatic synthesis; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/slct.201902403
• Languages: English
• ISSNs: 2365-6549

Abstract

Abstract: Laccase‐mediator systems (LMS) are extensively used both for degradation of various xenobiotics and synthesis of new compounds. In this work a laccase‐mediator system was applied to copolymerization of aniline and 2‐aminophenythyl alcohol on a 'soft' poly(2‐acrylamido‐2‐methyl‐1‐propansulfonic acid) (PAMPS) template. The one‐pot biocatalytic reaction resulted in obtaining a conducting copolymer/PAMPS complex with reactive aldehyde groups which enabled grafting the physiologically active compound 3, 4‐dihydroxy‐L‐phenylalanine (DOPA) to it. Abstract : A laccase‐mediator system was applied to copolymerization of aniline and 2‐aminophenythyl alcohol on a 'soft' poly(2‐acrylamido‐2‐methyl‐1‐propansulfonic acid) (PAMPS) template. The one‐pot biocatalytic reaction resulted in obtaining a conducting copolymer/PAMPS complex with reactive aldehyde groups which enabled grafting the physiologically active compound 3, 4‐dihydroxy‐L‐phenylalanine to it.